The town of Sandanski is located near the main international road E-79, section Sofia – Kulata – Thessaloniki. The railway Sofia – Kulata – Athens passes next to it.

The town is easily accessible to foreign tourists through the international airports in Sofia (160 km) and Thessaloniki (150 km) in the Republic of Greece. The tourists who have arrived at the airport of Thessaloniki have to cross the border checkpoint Promahonas – Kulata.